C7 antibody [030-113.7.5.4]

Catalogue Number: GTX42594-GTX

Manufacturer:	GeneTex
Preservative:	0.1% Sodium azide
Molecular Weight:	94
Physical state:	Liquid
Type:	Monoclonal Primary Antibody - Unconjugated
Alias:	complement C7
Shipping Condition:	Blue Ice
Unit(s):	100 ug
Host name:	Mouse
Clone:	030-113.7.5.4
Isotype:	IgG1
Immunogen:	Purified human C7.
Application:	ELISA, WB, NT, Inh

Overview
Datasheets

Description

Description: This gene encodes a serum glycoprotein that forms a membrane attack complex together with complement components C5b, C6, C8, and C9 as part of the terminal complement pathway of the innate immune system. The protein encoded by this gene contains a cholesterol-dependent cytolysin/membrane attack complex/perforin-like (CDC/MACPF) domain and belongs to a large family of structurally related molecules that form pores involved in host immunity and bacterial pathogenesis. This protein initiates membrane attack complex formation by binding the C5b-C6 subcomplex and inserts into the phospholipid bilayer, serving as a membrane anchor. Mutations in this gene are associated with a rare disorder called C7 deficiency. [provided by RefSeq, Nov 2016]

Additional Text

Gene Name

Gene ID

730

Uniprot ID

P10643

Purification

Protein A purified

Antibody Clonality

Monoclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Molecular Weight

Concentration

1 mg/ml

Application Notes

Neutralizing/Inhibition: . *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.

GTX42594 Datasheet

Price

£772.00

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Quantity
Unit Size

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