CD4 antibody [RM4-5] (FITC)

Catalogue Number: GTX43601-GTX

Manufacturer:	GeneTex
Preservative:	0.09% sodium azide
Molecular Weight:	51
Physical state:	Liquid
Type:	Monoclonal Primary Antibody - Conjugated
Alias:	CD4 antigen , L3T4 , Ly-4
Shipping Condition:	Blue Ice
Unit(s):	100 ug
Host name:	Rat
Clone:	RM4-5
Isotype:	IgG2a
Immunogen:	BALB/c mouse thymocytes
Application:	FC

Overview
Datasheets

Additional Text

Gene Name

CD4

Gene ID

12504

Concentration

0.5 mg/ml

Purification

Affinity Purified

Uniprot ID

P06332

Antibody Clonality

Monoclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Short Description

The RM4-5 antibody reacts with mouse CD4, a 55 kDa protein which acts as a co-receptor for the T cell receptor (TCR) in its interaction with MHC Class II molecules on antigen-presenting cells. The extracellular domain of CD4 binds to the beta2-domain of MHC Class II, while its cytoplasmic tail provides a binding site for the tyrosine kinase lck, facilitating the signaling cascade that initiates T cell activation. CD4 is typically expressed on thymocytes, certain mature T cell populations such as Th17 and T regulatory (Treg) cells, as well as on dendritic cells.

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4C. DO NOT FREEZE. Protect from light.

GTX43601 Datasheet

Price

£410.00

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