Collagen II antibody

Catalogue Number: GTX44078-GTX

Manufacturer:GeneTex
Molecular Weight:142
Physical state:Liquid
Type:Polyclonal Primary Antibody - Unconjugated
Alias:collagen type II alpha 1 chain , ANFH , AOM , COL11A3 , SEDC , STL1
Shipping Condition:Blue Ice
Unit(s): 100 ul
Host name: Rabbit
Clone:
Isotype: IgG
Immunogen: Collagen Type II extracted and purified from human cartilage.
Application: ELISA, ICC, IF, IHC-P, RIA, IHC-Fr

Description

Description: This gene encodes the alpha-1 chain of type II collagen, a fibrillar collagen found in cartilage and the vitreous humor of the eye. Mutations in this gene are associated with achondrogenesis, chondrodysplasia, early onset familial osteoarthritis, SED congenita, Langer-Saldino achondrogenesis, Kniest dysplasia, Stickler syndrome type I, and spondyloepimetaphyseal dysplasia Strudwick type. In addition, defects in processing chondrocalcin, a calcium binding protein that is the C-propeptide of this collagen molecule, are also associated with chondrodysplasia. There are two transcripts identified for this gene. [provided by RefSeq, Jul 2008]

Additional Text

Gene Name

COL2A1

Uniprot ID

P02458

Gene ID

1280

Purification

Ion Exchange

Antibody Clonality

Polyclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Application Notes

IHC-P: 1:1,000. IHC-Fr: 1:80. ELISA: 1:200. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.