PRMT6 antibody, Internal
Catalogue Number: GTX47433-GTX
GTX47433 Image
GTX47433 Image
GTX47433 Image
ChIP analysis of HCT116 cells using GTX47433 PRMT6 antibody. Use 0.5µg antibody GTX47433 PRMT6 antibody for ChIP assay. Quiescent human colon carcinoma HCT116 cultures were treated with 10% FBS for three time points (0, 15, 30min) or (0, 30, 60min) were used in Matrix-ChIP and real-time PCR assays at EGR1 gene (Exon1) and 15kb upstream site.
GTX47433 Image
WB analysis of 293T cells using GTX47433 PRMT6 antibody at 0.2-1µg/ml.
| Manufacturer: | GeneTex |
| Preservative: | 0.09% sodium azide |
| Molecular Weight: | 42 |
| Physical state: | Liquid |
| Type: | Polyclonal Primary Antibody - Unconjugated |
| Alias: | protein arginine methyltransferase 6 , HRMT1L6 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 50 ug |
| Host name: | Rabbit |
| Clone: | |
| Isotype: | IgG |
| Immunogen: | A synthetic peptide corresponding to an Internal region of Human PRMT6 |
| Application: | ChIP, WB |
Description
Description: The protein encoded by this gene belongs to the arginine N-methyltransferase family, which catalyze the sequential transfer of methyl group from S-adenosyl-L-methionine to the side chain nitrogens of arginine residues within proteins, to form methylated arginine derivatives and S-adenosyl-L-homocysteine. This protein can catalyze both, the formation of omega-N monomethylarginine and asymmetrical dimethylarginine, with a strong preference for the latter. It specifically mediates the asymmetric dimethylation of Arg2 of histone H3, and the methylated form represents a specific tag for epigenetic transcriptional repression. This protein also forms a complex with, and methylates DNA polymerase beta, resulting in stimulation of polymerase activity by enhancing DNA binding and processivity. [provided by RefSeq, Sep 2011]
Additional Text
Gene Name
PRMT6
Uniprot ID
Q96LA8
Molecular Weight
42
Concentration
0.5-1 mg/ml
Purification
Affinity Purified
Gene ID
55170
Antibody Clonality
Polyclonal
Note
For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption
Storage Note
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
Application Notes
WB: 0.2-2.5 µg/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
GTX47433 Datasheet
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