FBXO32 antibody (FITC)

Catalogue Number: GTX47815-GTX

Manufacturer:GeneTex
Preservative:0.02% Sodium azide|0.02% Sodium azide
Molecular Weight:42
Physical state:Liquid
Type:Polyclonal Primary Antibody - Conjugated
Alias:F-box protein 32 , Fbx32 , MAFbx
Shipping Condition:Blue Ice
Unit(s): 50 ug
Host name: Rabbit
Clone:
Isotype: IgG
Immunogen: Synthetic peptide taken within amino acid region 240-280 on Atr1 protein.
Application: ELISA, IP, WB, IHC

Description

Description: This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and contains an F-box domain. This protein is highly expressed during muscle atrophy, whereas mice deficient in this gene were found to be resistant to atrophy. This protein is thus a potential drug target for the treatment of muscle atrophy. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jun 2011]

Additional Text

Molecular Weight

42

Uniprot ID

Q969P5

Gene Name

FBXO32

Gene ID

114907

Purification

Purified

Concentration

0.64-0.72 mg/ml

Antibody Clonality

Polyclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles. Protect from light.