Vitamin K epoxide reductase antibody (FITC)

Catalogue Number: GTX47836-GTX

Manufacturer:	GeneTex
Preservative:	0.02% Sodium azide\|0.02% Sodium azide
Molecular Weight:	18
Physical state:	Liquid
Type:	Polyclonal Primary Antibody - Conjugated
Alias:	vitamin K epoxide reductase complex subunit 1 , EDTP308 , MST134 , MST576 , VKCFD2 , VKOR
Shipping Condition:	Blue Ice
Unit(s):	50 ug
Host name:	Rabbit
Clone:
Isotype:	IgG
Immunogen:	Synthetic peptide taken within amino acid region 10-60 on human VKORC1 protein.
Application:	ELISA, IP, WB, IHC

Overview
Datasheets

Description

Description: This gene encodes the catalytic subunit of the vitamin K epoxide reductase complex, which is responsible for the reduction of inactive vitamin K 2,3-epoxide to active vitamin K in the endoplasmic reticulum membrane. Vitamin K is a required co-factor for carboxylation of glutamic acid residues by vitamin K-dependent gamma-carboxylase in blood-clotting enzymes. Allelic variation in this gene is associated with vitamin k-dependent clotting factors combined deficiency of 2, and increased resistance or sensitivity to warfarin, an inhibitor of vitamin K epoxide reductase. Pseudogenes of this gene are located on chromosomes 1 and X. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2015]

Additional Text

Gene Name

VKORC1

Uniprot ID

Q9BQB6

Gene ID

79001

Purification

Purified

Antibody Clonality

Polyclonal

Concentration

0.65-0.70 mg/ml

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Molecular Weight

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles. Protect from light.

GTX47836 Datasheet

Price

£386.00

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