PGAP3 antibody (N-terminal) (FITC)

Catalogue Number: GTX47865-GTX

Manufacturer:GeneTex
Preservative:0.02% Sodium azide|0.02% Sodium azide
Molecular Weight:36
Physical state:Liquid
Type:Polyclonal Primary Antibody - Conjugated
Alias:post-GPI attachment to proteins 3 , AGLA546 , CAB2 , PERLD1 , PP1498 , hCOS16
Shipping Condition:Blue Ice
Unit(s): 50 ug
Host name: Rabbit
Clone:
Isotype: IgG
Immunogen: Synthetic peptide taken within amino acid region 1-50 on human PGAP3 protein.
Application: ELISA, IP, WB, IHC

Description

Description: This gene encodes a glycosylphosphatidylinositol (GPI)-specific phospholipase that primarily localizes to the Golgi apparatus. This ubiquitously expressed gene is predicted to encode a seven-transmembrane protein that removes unsaturated fatty acids from the sn-2 position of GPI. The remodeling of the constituent fatty acids on GPI is thought to be important for the proper association between GPI-anchored proteins and lipid rafts. The tethering of proteins to plasma membranes via posttranslational GPI-anchoring is thought to play a role in protein sorting and trafficking. Mutations in this gene cause an autosomal recessive form of neurologic hyperphosphatasia with cognitive disability (HPMRS4). Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2017]

Additional Text

Gene Name

PGAP3

Uniprot ID

Q96FM1

Gene ID

93210

Purification

Purified

Antibody Clonality

Polyclonal

Concentration

0.50-0.75 mg/ml

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Molecular Weight

36

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles. Protect from light.