Human VEGFD protein

Catalogue Number: GTX48447-PRO-GTX

Manufacturer:GeneTex
Physical state:Lyophilized
Type:Growth Factors
Alias:vascular endothelial growth factor D , FIGF , VEGF-D
Host Cell:HEK293 cells
Shipping Condition:Blue Ice
Unit(s): 10 ug
Application: FA

Description

Description: The protein encoded by this gene is a member of the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family and is active in angiogenesis, lymphangiogenesis, and endothelial cell growth. This secreted protein undergoes a complex proteolytic maturation, generating multiple processed forms which bind and activate VEGFR-2 and VEGFR-3 receptors. This protein is structurally and functionally similar to vascular endothelial growth factor C. Read-through transcription has been observed between this locus and the upstream PIR (GeneID 8544) locus. [provided by RefSeq, Feb 2011]

Additional Text

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Application Notes

Measured by its ability to bind immobilized recombinant human Neuropilin-1 in an ELISA.

Short Description

Recombinant human VEGF-D is a 26.2 kDa non-disulfide linked homodimeric protein consisting of two 117 amino acid polypeptide chains. Due to glycosylation the protein migrates as a 20.0-22.0 kDa band under non-reducing condition.

Storage Note

Store at -20C or below. After reconstitution, keep as concentrated solution. Avoid freeze-thaw cycles.