TDP43 antibody (DyLight 488)

Catalogue Number: GTX48593-GTX

Manufacturer:GeneTex
Preservative:0.05% Sodium azide
Physical state:Liquid
Type:Polyclonal Primary Antibody - Conjugated
Alias:TAR DNA binding protein , ALS10 , TDP-43
Shipping Condition:Blue Ice
Unit(s): 50 ul
Host name: Rabbit
Clone:
Isotype: IgG
Immunogen: A synthetic peptide to a C-terminal region [within residues 350-414] of the human TARDBP protein. [Swiss-Prot# Q13148]
Application: ICC, IF, WB, IHC

Description

Description: HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. The protein encoded by this gene is a transcriptional repressor that binds to chromosomally integrated TAR DNA and represses HIV-1 transcription. In addition, this protein regulates alternate splicing of the CFTR gene. A similar pseudogene is present on chromosome 20. [provided by RefSeq]

Additional Text

Gene Name

TARDBP

Purification

Affinity Purified

Gene ID

23435

UniProt ID

Q13148

Molecular Weight

45

Antibody Clonality

Polyclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption