Rad9 (phospho Ser328) antibody

Catalogue Number: GTX50885-GTX

Manufacturer:GeneTex
Preservative:0.09% sodium azide
Molecular Weight:43
Physical state:Liquid
Type:Polyclonal Primary Antibody - Unconjugated
Alias:RAD9 checkpoint clamp component A , RAD9
Shipping Condition:Blue Ice
Unit(s): 400 ul
Host name: Rabbit
Clone:
Isotype: IgG
Immunogen: KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S328 of human RAD9.
Application: IHC-P, WB, DB

Description

Description: This gene product is highly similar to Schizosaccharomyces pombe rad9, a cell cycle checkpoint protein required for cell cycle arrest and DNA damage repair. This protein possesses 3' to 5' exonuclease activity, which may contribute to its role in sensing and repairing DNA damage. It forms a checkpoint protein complex with RAD1 and HUS1. This complex is recruited by checkpoint protein RAD17 to the sites of DNA damage, which is thought to be important for triggering the checkpoint-signaling cascade. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011]

Additional Text

Gene ID

5883

Gene Name

RAD9A

Uniprot ID

Q99638

Antibody Clonality

Polyclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Modification

Phosphorylated, Ser328

Molecular Weight

43

Purification

Affinity Purified; Protein A Purified

Application Notes

WB: 1:1000. IHC-P: 1:50-1:100. Dot: 1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.