IL12 antibody [31H23]

Catalogue Number: GTX52547-GTX

Manufacturer:GeneTex
Preservative:no preservative|No preservative
Molecular Weight:25
Physical state:Liquid
Type:Monoclonal Primary Antibody - Unconjugated
Alias:CLMF , IL12A , NFSK , NKSF1 , P35 , interleukin 12A , IL12 p35
Shipping Condition:Blue Ice
Unit(s): 50 ug
Host name: Mouse
Clone: 31H23
Isotype: IgG1
Immunogen: Recombinant Human IL-12 p70
Application: WB, NT, Inh

Description

Description: This gene encodes a subunit of a cytokine that acts on T and natural killer cells, and has a broad array of biological activities. The cytokine is a disulfide-linked heterodimer composed of the 35-kD subunit encoded by this gene, and a 40-kD subunit that is a member of the cytokine receptor family. This cytokine is required for the T-cell-independent induction of interferon (IFN)-gamma, and is important for the differentiation of both Th1 and Th2 cells. The responses of lymphocytes to this cytokine are mediated by the activator of transcription protein STAT4. Nitric oxide synthase 2A (NOS2A/NOS2) is found to be required for the signaling process of this cytokine in innate immunity. [provided by RefSeq, Jul 2008]

Additional Text

Gene ID

3592

Gene Name

IL12A

Uniprot ID

P29459

Concentration

200 ug/ml

Purification

Protein G purified

Antibody Clonality

Monoclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Molecular Weight

25

Application Notes

WB: 1:100 - 1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.