CD86 antibody [7F35]

Catalogue Number: GTX52552-GTX

Manufacturer:GeneTex
Preservative:no preservative|No preservative
Molecular Weight:38
Physical state:Liquid
Type:Monoclonal Primary Antibody - Unconjugated
Alias:B7.2 , B70 , B72 , CD28LG2 , CD86 , CD86 molecule , LAB72 , B7-2
Shipping Condition:Blue Ice
Unit(s): 50 ug
Host name: Mouse
Clone: 7F35
Isotype: IgG1
Immunogen: Human recombinant CD86 EC domian
Application: FC, WB, NT, Inh

Description

Description: This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms.[provided by RefSeq, May 2011]

Additional Text

Gene Name

CD86

Purification

Protein G purified

Concentration

500 ug/ml

Gene ID

942

Uniprot ID

P42081

Antibody Clonality

Monoclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Molecular Weight

38

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.

Application Notes

WB: 1:500 - 1:1000. FCM: 1:50 - 1:100. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.