BMP10 antibody [5L26]

Catalogue Number: GTX52564-GTX

Manufacturer:GeneTex
Preservative:no preservative|No preservative
Molecular Weight:48
Physical state:Liquid
Type:Monoclonal Primary Antibody - Unconjugated
Alias:BMP10 , bone morphogenetic protein 10
Shipping Condition:Blue Ice
Unit(s): 50 ug
Host name: Mouse
Clone: 5L26
Isotype: IgG2
Immunogen: Human recombinant BMP-10
Application: WB, NT, Inh

Description

Description: This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate the mature protein, which binds to the activin receptor-like kinase 1 (ALK1) and plays important roles in cardiovascular development including cardiomyocyte proliferation and regulation of heart size, closure of the ductus arteriosus, angiogenesis and ventricular trabeculation. [provided by RefSeq, Aug 2016]

Additional Text

Gene ID

27302

Uniprot ID

O95393

Gene Name

BMP10

Purification

Protein G purified

Concentration

500 ug/ml

Molecular Weight

48

Antibody Clonality

Monoclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Application Notes

WB: 1:500 - 1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.