BMP6 antibody [10H10]

Catalogue Number: GTX52569-GTX

Manufacturer:GeneTex
Preservative:no preservative|No preservative
Physical state:Liquid
Type:Monoclonal Primary Antibody - Unconjugated
Alias:BMP6 , VGR , VGR1 , bone morphogenetic protein 6
Shipping Condition:Blue Ice
Unit(s): 50 ug
Host name: Mouse
Clone: 10H10
Isotype: IgG2
Immunogen: Human recombinant BMP-6
Application: WB, NT, Inh

Description

Description: This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein regulates a wide range of biological processes including iron homeostasis, fat and bone development, and ovulation. Differential expression of this gene may be associated with progression of breast and prostate cancer. Mutations in this gene may be associated with iron overload in human patients. [provided by RefSeq, Jul 2016]

Additional Text

Gene ID

654

Gene Name

BMP6

Purification

Protein G purified

Concentration

500 ug/ml

Antibody Clonality

Monoclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Application Notes

WB: 1:500 - 1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

UniProt ID

P22004, Q4VBA3

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.