CD3 epsilon antibody [3F43]

Catalogue Number: GTX52620-GTX

Manufacturer:GeneTex
Preservative:no preservative|No preservative
Molecular Weight:23
Physical state:Liquid
Type:Monoclonal Primary Antibody - Unconjugated
Alias:CD3E , CD3e molecule , IMD18 , T3E , TCRE , CD3 epsilon
Shipping Condition:Blue Ice
Unit(s): 50 ug
Host name: Mouse
Clone: 3F43
Isotype: IgG1
Immunogen: Human recombinant CD3 ε
Application: FC, IHC-Fr, Act

Description

Description: The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women. [provided by RefSeq, Jul 2008]

Additional Text

Gene Name

CD3E

Gene ID

916

Uniprot ID

P07766

Purification

Protein G purified

Concentration

500 ug/ml

Antibody Clonality

Monoclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.

Application Notes

IHC-Fr: 1:50 - 1:100. FCM: 1:50 - 1:100. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.