CD30 antibody [5K28]

Catalogue Number: GTX52622-GTX

Manufacturer:GeneTex
Preservative:no preservative|No preservative
Molecular Weight:64
Physical state:Liquid
Type:Monoclonal Primary Antibody - Unconjugated
Alias:CD30 , D1S166E , Ki1 , TNF receptor superfamily member 8 , TNFRSF8
Shipping Condition:Blue Ice
Unit(s): 100 ug
Host name: Mouse
Clone: 5K28
Isotype: IgG2
Immunogen: Human recombinant TNFRSF8 EC domain
Application: FC, WB, Act

Description

Description: The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is expressed by activated, but not by resting, T and B cells. TRAF2 and TRAF5 can interact with this receptor, and mediate the signal transduction that leads to the activation of NF-kappaB. This receptor is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]

Additional Text

Gene Name

TNFRSF8

Purification

Protein G purified

Concentration

500 ug/ml

Gene ID

943

Uniprot ID

P28908

Molecular Weight

64

Antibody Clonality

Monoclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.

Application Notes

WB: 1:500 - 1:1000. FCM: 1:20 - 1:100. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.