DR5 antibody [10B4]

Catalogue Number: GTX53032-GTX

Manufacturer:GeneTex
Preservative:no preservative|No preservative
Molecular Weight:48
Physical state:Liquid
Type:Monoclonal Primary Antibody - Unconjugated
Alias:CD262 , DR5 , KILLER , KILLER/DR5 , TNF receptor superfamily member 10b , TNFRSF10B , TRAILR2 , TRICK2 , TRICK2A , TRICK2B , TRICKB , ZTNFR9 , TRAIL-R2
Shipping Condition:Blue Ice
Unit(s): 100 ug
Host name: Mouse
Clone: 10B4
Isotype: IgG1
Immunogen: Human recombinant TNFRSF10B EC domain
Application: Act

Description

Description: The protein encoded by this gene is a member of the TNF-receptor superfamily, and contains an intracellular death domain. This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and transduces an apoptosis signal. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. Two transcript variants encoding different isoforms and one non-coding transcript have been found for this gene. [provided by RefSeq, Mar 2009]

Additional Text

Gene Name

TNFRSF10B

Uniprot ID

O14763

Gene ID

8795

Purification

Protein G purified

Concentration

500 ug/ml

Antibody Clonality

Monoclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Application Notes

*Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.