DR5 antibody [10B4]

Catalogue Number: GTX53032-GTX

Manufacturer:GeneTex
Preservative:No preservative
Physical state:Liquid
Type:Monoclonal Primary Antibody - Unconjugated
Alias:CD262 , DR5 , KILLER , KILLER/DR5 , TNF receptor superfamily member 10b , TNFRSF10B , TRAILR2 , TRICK2 , TRICK2A , TRICK2B , TRICKB , ZTNFR9 , TRAIL-R2
Shipping Condition:Blue Ice
Unit(s): 100 ug
Host name: Mouse
Clone: 10B4
Isotype: IgG1
Immunogen: Human recombinant TNFRSF10B EC domain
Application: Act

Description

Description: The protein encoded by this gene is a member of the TNF-receptor superfamily, and contains an intracellular death domain. This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and transduces an apoptosis signal. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. Two transcript variants encoding different isoforms and one non-coding transcript have been found for this gene. [provided by RefSeq, Mar 2009]

Additional Text

Gene Name

TNFRSF10B

Uniprot ID

O14763

Gene ID

8795

Purification

Protein G purified

Concentration

500 ug/ml

Molecular Weight

48

Antibody Clonality

Monoclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Application Notes

*Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.