SEMA3C antibody [29U11]

Catalogue Number: GTX53062-GTX

Manufacturer:GeneTex
Preservative:no preservative|No preservative
Molecular Weight:85
Physical state:Liquid
Type:Monoclonal Primary Antibody - Unconjugated
Alias:SEMA3C , SEMAE , SemE , semaphorin 3C
Shipping Condition:Blue Ice
Unit(s): 100 ug
Host name: Rat
Clone: 29U11
Isotype: IgG2
Immunogen: Recombinant Human Semaphorin 3C
Application: WB, IHC

Description

Description: This gene encodes a secreted glycoprotein that belongs to the semaphorin class 3 family of neuronal guidance cues. The encoded protein contains an N-terminal sema domain, integrin and immunoglobulin-like domains, and a C-terminal basic domain. Homodimerization and proteolytic cleavage of the C-terminal propeptide are necessary for the function of the encoded protein. It binds a neuropilin co-receptor before forming a heterotrimeric complex with an associated plexin. An increase in the expression of this gene correlates with an increase in cancer cell invasion and adhesion. Naturally occurring mutations in this gene are associated with Hirschsprung disease. [provided by RefSeq, May 2017]

Additional Text

Gene Name

SEMA3C

Gene ID

10512

Uniprot ID

Q99985

Concentration

200 ug/ml

Purification

Protein G purified

Molecular Weight

85

Antibody Clonality

Monoclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Application Notes

WB: 1:500 - 1:1000. IHC: 1:100 - 1:200. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.