TNF Receptor I antibody [6F13]

Catalogue Number: GTX53102-GTX

Manufacturer:GeneTex
Preservative:no preservative|No preservative
Molecular Weight:50
Physical state:Liquid
Type:Monoclonal Primary Antibody - Unconjugated
Shipping Condition:Blue Ice
Unit(s): 100 ug
Host name: Armenian Hamster
Clone: 6F13
Isotype: IgG
Immunogen: Recombinant extracellular domain of mouse
Application: ELISA, FC, IP, WB

Description

Description: This gene encodes a member of the TNF receptor superfamily of proteins. The encoded receptor is found in membrane-bound and soluble forms that interact with membrane-bound and soluble forms, respectively, of its ligand, tumor necrosis factor alpha. Binding of membrane-bound tumor necrosis factor alpha to the membrane-bound receptor induces receptor trimerization and activation, which plays a role in cell survival, apoptosis, and inflammation. Proteolytic processing of the encoded receptor results in release of the soluble form of the receptor, which can interact with free tumor necrosis factor alpha to inhibit inflammation. Mice lacking a functional copy of this gene exhibit impaired immune function. [provided by RefSeq, Sep 2016]

Additional Text

Gene Name

TNFRSF1A

Uniprot ID

P25118

Purification

Protein A/G Purified

Concentration

500 ug/ml

Gene ID

21937

Molecular Weight

50

Antibody Clonality

Monoclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.