TGF beta Receptor I antibody [3A11]

Catalogue Number: GTX53107-GTX

Manufacturer:GeneTex
Preservative:no preservative|No preservative
Molecular Weight:56
Physical state:Liquid
Type:Monoclonal Primary Antibody - Unconjugated
Shipping Condition:Blue Ice
Unit(s): 100 ug
Host name: Rat
Clone: 3A11
Isotype: IgG2
Immunogen: Mouse ALK5 extra cellular domain
Application: IHC-P, WB

Description

Description: This gene encodes a member of the transforming growth factor beta (TGF-beta) receptor family of proteins. These proteins comprise one component of the TGF-beta signaling pathway, which transduces extracellular signals into gene expression changes to regulate a wide range of cellular responses, including proliferation, migration, differentiation and apoptosis. Homozygous knockout mice for this gene exhibit impaired angiogenesis and embryonic lethality. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2015]

Additional Text

Gene Name

TGFBR1

Uniprot ID

Q64729

Concentration

200 ug/ml

Purification

Protein G purified

Molecular Weight

56

Gene ID

21812

Antibody Clonality

Monoclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Application Notes

WB: 1:800 - 1:2000. IHC-P: 1:50 - 1:100. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.