VEGF Receptor 2 antibody [6B11]

Catalogue Number: GTX53462-GTX

Manufacturer:GeneTex
Preservative:no preservative|No preservative
Molecular Weight:152
Physical state:Liquid
Type:Monoclonal Primary Antibody - Unconjugated
Alias:CD309 , FLK1 , KDR , VEGFR , VEGFR2 , kinase insert domain receptor , VEGF Receptor 2
Shipping Condition:Blue Ice
Unit(s): 100 ug
Host name: Mouse
Clone: 6B11
Isotype: IgG1
Immunogen: hVEGFR2 N-terminal fragment (N30-200)
Application: WB, NT, Inh, Act

Description

Description: Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc.. Mutations of this gene are implicated in infantile capillary hemangiomas. [provided by RefSeq, May 2009]

Additional Text

Gene Name

KDR

Gene ID

3791

Uniprot ID

P35968

Purification

Protein G purified

Molecular Weight

152

Antibody Clonality

Monoclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.