Human RSPO1 protein (active)
Catalogue Number: GTX53852-PRO-GTX
| Manufacturer: | GeneTex |
| Physical state: | Lyophilized |
| Type: | Bioactive Proteins |
| Alias: | R-spondin 1 , CRISTIN3 , RSPO |
| Host Cell: | CHO Cells |
| Shipping Condition: | Blue Ice |
| Unit(s): | 20 ug |
| Application: | FA |
Additional Text
Gene ID
284654
Uniprot ID
Q2MKA7
Gene Name
RSPO1
Note
For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Application Notes
Assay #1: R-Spondin-1 enhances BMP-2-mediated differentiation of MC3T3-E1 cells. The expected ED₅₀ is 1.0-3.0 µg/ml. Assay #2: Measured by its ability to induce Topflash reporter activity in HEK293 TCF/LEF Luc reporter cells. The ED₅₀ for this effect is typically 0.6-1.0 µg/ml in the presence of 50 ng/ml recombinant human BMP-2.
Short Description
Recombinant human R-Spondin-1 is a 26.7 kDa protein consisting of 243 amino acid residues. Due to glycosylation, R-Spondin-1 migrates at an apparent molecular weight of approximately 40.0 kDa by SDS PAGE analysis under reducing conditions. Verified by N-terminal and Mass Spectrometry analyses (when applicable).
Storage Note
Store at -20C or below. After reconstitution, keep as concentrated solution. Aliquot and avoid freeze-thaw cycles.
GTX53852-PRO Datasheet
SUPPORT
outstanding technical support
PRODUCT
we offer a full product guarantee
DELIVERY
we offer free delivery to UK universities and non profit organisations