Plasma Kallikrein 1B antibody

Catalogue Number: GTX54292-GTX

Manufacturer:GeneTex
Preservative:0.02% Sodium azide|0.02% Sodium azide
Molecular Weight:71
Physical state:Liquid
Type:Polyclonal Primary Antibody - Unconjugated
Alias:kallikrein B1 , KLK3 , PKK , PKKD , PPK
Shipping Condition:Blue Ice
Unit(s): 100 ug
Host name: Rabbit
Clone:
Isotype: IgG
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 20-300 of human KLKB1 (NP_000883.2).
Application: IHC-P, WB

Description

Description: This gene encodes a glycoprotein that participates in the surface-dependent activation of blood coagulation, fibrinolysis, kinin generation and inflammation. The encoded preproprotein present in plasma as a non-covalent complex with high molecular weight kininogen undergoes proteolytic processing mediated by activated coagulation factor XII to generate a disulfide-linked, heterodimeric serine protease comprised of heavy and light chains. Certain mutations in this gene cause prekallikrein deficiency. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2016]

Additional Text

Gene ID

3818

Gene Name

KLKB1

Uniprot ID

P03952

Purification

Affinity Purified

Molecular Weight

71

Antibody Clonality

Polyclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Application Notes

WB: 1:500 - 1:2000. IHC-P: 1:50 - 1:200. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.