ITGB3BP antibody

Catalogue Number: GTX54299-GTX

Manufacturer:	GeneTex
Preservative:	0.02% Sodium azide\|0.02% Sodium azide
Molecular Weight:	20
Physical state:	Liquid
Type:	Polyclonal Primary Antibody - Unconjugated
Alias:	integrin subunit beta 3 binding protein , CENP-R , CENPR , HSU37139 , NRIF3 , TAP20
Shipping Condition:	Blue Ice
Unit(s):	100 ug
Host name:	Rabbit
Clone:
Isotype:	IgG
Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 1-111 of human ITGB3BP (NP_055103.3).
Application:	WB

Overview
Datasheets

Description

Description: This gene encodes a transcriptional coregulator that binds to and enhances the activity of members of the nuclear receptor families, thyroid hormone receptors and retinoid X receptors. This protein also acts as a corepressor of NF-kappaB-dependent signaling. This protein induces apoptosis in breast cancer cells through a caspase 2-mediated signaling pathway. This protein is also a component of the centromere-specific histone H3 variant nucleosome associated complex (CENP-NAC) and may be involved in mitotic progression by recruiting the histone H3 variant CENP-A to the centromere. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2011]

Additional Text

Gene Name

ITGB3BP

Molecular Weight

Uniprot ID

Q13352

Gene ID

23421

Purification

Affinity Purified

Antibody Clonality

Polyclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Application Notes

WB: 1:500 - 1:2000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.

GTX54299 Datasheet

Price

£386.00

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Quantity
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