TNF Receptor I antibody [MR1-2]

Catalogue Number: GTX54416-GTX

Manufacturer:	GeneTex
Preservative:	no preservative\|No preservative
Molecular Weight:	50
Physical state:	Liquid
Type:	Monoclonal Primary Antibody - Unconjugated
Alias:	CD120a,FPF,TBP1,TNF receptor superfamily member 1A,TNFAR,TNFR,TNFR1,TNFR55,TNFR60,TNFRI,TNFRSF1A,p55,p55R,p60,TNF receptor I,TNF-R1,TNF-RI
Shipping Condition:	Blue Ice
Storage Condition:	2-8°C
Unit(s):	50 ug
Host name:	Mouse
Clone:	MR1-2
Isotype:	IgG1
Immunogen:	Extracellular part of TNF-R55
Application:	FC, FA

Overview
Datasheets

Description

Description: This gene encodes a member of the TNF receptor superfamily of proteins. The encoded receptor is found in membrane-bound and soluble forms that interact with membrane-bound and soluble forms, respectively, of its ligand, tumor necrosis factor alpha. Binding of membrane-bound tumor necrosis factor alpha to the membrane-bound receptor induces receptor trimerization and activation, which plays a role in cell survival, apoptosis, and inflammation. Proteolytic processing of the encoded receptor results in release of the soluble form of the receptor, which can interact with free tumor necrosis factor alpha to inhibit inflammation. Mutations in this gene underlie tumor necrosis factor receptor-associated periodic syndrome (TRAPS), characterized by fever, abdominal pain and other features. Mutations in this gene may also be associated with multiple sclerosis in human patients. [provided by RefSeq, Sep 2016]

Additional Text

Uniprot ID

P19438

Gene Name

TNFRSF1A

Gene ID

7132

Purification

Protein G purified

Concentration

100 ug/ml

Antibody Clonality

Monoclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4C.

GTX54416 Datasheet

Price

£386.00

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Quantity
Unit Size

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