TNF Receptor II antibody [MR2-1]

Catalogue Number: GTX54417-GTX

Manufacturer:	GeneTex
Preservative:	no preservative\|No preservative
Molecular Weight:	48
Physical state:	Liquid
Type:	Monoclonal Primary Antibody - Unconjugated
Alias:	CD120b,TBPII,TNF receptor superfamily member 1B,TNFBR,TNFR1B,TNFR2,TNFR75,TNFR80,TNFRII,TNFRSF1B,p75,p75TNFR,TNF receptor II
Shipping Condition:	Blue Ice
Storage Condition:	2-8°C
Unit(s):	50 ug
Host name:	Mouse
Clone:	MR2-1
Isotype:	IgG1
Immunogen:
Application:	ELISA, FC, ICC, IF, IP, WB, IHC-Fr, FA

Overview
Datasheets

Description

Description: The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein and TNF-receptor 1 form a heterocomplex that mediates the recruitment of two anti-apoptotic proteins, c-IAP1 and c-IAP2, which possess E3 ubiquitin ligase activity. The function of IAPs in TNF-receptor signalling is unknown, however, c-IAP1 is thought to potentiate TNF-induced apoptosis by the ubiquitination and degradation of TNF-receptor-associated factor 2, which mediates anti-apoptotic signals. Knockout studies in mice also suggest a role of this protein in protecting neurons from apoptosis by stimulating antioxidative pathways. [provided by RefSeq, Jul 2008]

Additional Text

Uniprot ID

P20333

Gene Name

TNFRSF1B

Gene ID

7133

Concentration

100 ug/ml

Molecular Weight

Purification

Purified

Antibody Clonality

Monoclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4C.

GTX54417 Datasheet

Price

£386.00

-

Quantity
Unit Size

Find out about delivery