C5a/C5a des-Arg antibody [2952]

Catalogue Number: GTX54440-GTX

Manufacturer:	GeneTex
Preservative:	no preservative\|No preservative
Molecular Weight:	188
Physical state:	Liquid
Type:	Monoclonal Primary Antibody - Unconjugated
Alias:	C5,C5D,C5a,C5b,CPAMD4,ECLZB,complement C5,Complement C5
Shipping Condition:	Blue Ice
Storage Condition:	2-8°C
Unit(s):	50 ug
Host name:	Mouse
Clone:	2952
Isotype:	IgG1
Immunogen:
Application:	ELISA, WB, IHC-Fr, FA

Overview
Datasheets

Description

Description: This gene encodes a component of the complement system, a part of the innate immune system that plays an important role in inflammation, host homeostasis, and host defense against pathogens. The encoded preproprotein is proteolytically processed to generate multiple protein products, including the C5 alpha chain, C5 beta chain, C5a anaphylatoxin and C5b. The C5 protein is comprised of the C5 alpha and beta chains, which are linked by a disulfide bridge. Cleavage of the alpha chain by a convertase enzyme results in the formation of the C5a anaphylatoxin, which possesses potent spasmogenic and chemotactic activity, and the C5b macromolecular cleavage product, a subunit of the membrane attack complex (MAC). Mutations in this gene cause complement component 5 deficiency, a disease characterized by recurrent bacterial infections. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2015]

Additional Text

Uniprot ID

P01031

Gene Name

Gene ID

727

Concentration

100 ug/ml

Molecular Weight

188

Purification

Purified

Antibody Clonality

Monoclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4C.

GTX54440 Datasheet

Price

£374.00

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Quantity
Unit Size

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