CD46 antibody [M177]
Catalogue Number: GTX54447-GTX
GTX54447 Image
GTX54447 Image
GTX54447 Image
FACS analysis of THP-1 cells using GTX54447 CD46 antibody [M177]. Red : Negative control Black : Cells only control Blue : Primary antibody Antibody amount : 10 µg
GTX54447 Image
IHC-Fr analysis of human kidney tissue sections using GTX54447 CD46 antibody [M177]. The antibody appeared to give a specific staining in glomeruli, juxtaglomerular apparatus and tubuli. Dilution : 1:4000
| Manufacturer: | GeneTex |
| Preservative: | no preservative|No preservative |
| Molecular Weight: | 44 |
| Physical state: | Liquid |
| Type: | Monoclonal Primary Antibody - Unconjugated |
| Alias: | AHUS2,CD46,CD46 molecule,MCP,MIC10,TLX,TRA2.10 |
| Shipping Condition: | Blue Ice |
| Storage Condition: | 2-8°C |
| Unit(s): | 50 ug |
| Host name: | Mouse |
| Clone: | M177 |
| Isotype: | IgG1 |
| Immunogen: | Purified MCP |
| Application: | ELISA, FC, IP, WB, IHC-Fr, FA |
Description
Description: The protein encoded by this gene is a type I membrane protein and is a regulatory part of the complement system. The encoded protein has cofactor activity for inactivation of complement components C3b and C4b by serum factor I, which protects the host cell from damage by complement. In addition, the encoded protein can act as a receptor for the Edmonston strain of measles virus, human herpesvirus-6, and type IV pili of pathogenic Neisseria. Finally, the protein encoded by this gene may be involved in the fusion of the spermatozoa with the oocyte during fertilization. Mutations at this locus have been associated with susceptibility to hemolytic uremic syndrome. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jun 2010]
Additional Text
Gene Name
CD46
Purification
Protein G purified
Concentration
100 ug/ml
Gene ID
4179
Molecular Weight
44
Uniprot ID
P15529
Antibody Clonality
Monoclonal
Note
For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption
Application Notes
*Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Storage Note
Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4C.
GTX54447 Datasheet
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