OLR1 / LOX-1 antibody [23C11]

Catalogue Number: GTX54456-GTX

Manufacturer:	GeneTex
Preservative:	no preservative\|No preservative
Molecular Weight:	31
Physical state:	Liquid
Type:	Monoclonal Primary Antibody - Unconjugated
Alias:	CLEC8A,LOX1,LOXIN,OLR1,SCARE1,SLOX1,oxidized low density lipoprotein receptor 1,LOX-1
Shipping Condition:	Blue Ice
Storage Condition:	2-8°C
Unit(s):	50 ug
Host name:	Mouse
Clone:	23C11
Isotype:	IgG1
Immunogen:	Fusion protein of extracellular domain (aa 71-273) of human LOX-1 with murine Fcγ1 (LOX-1-muFc) produced in PEAK cells
Application:	FC, ICC, IF, IHC-P, NT, Inh

Overview
Datasheets

Description

Description: This gene encodes a low density lipoprotein receptor that belongs to the C-type lectin superfamily. This gene is regulated through the cyclic AMP signaling pathway. The encoded protein binds, internalizes and degrades oxidized low-density lipoprotein. This protein may be involved in the regulation of Fas-induced apoptosis. This protein may play a role as a scavenger receptor. Mutations of this gene have been associated with atherosclerosis, risk of myocardial infarction, and may modify the risk of Alzheimer's disease. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Feb 2010]

Additional Text

Gene Name

OLR1

Concentration

100 ug/ml

Gene ID

4973

Purification

Purified

Uniprot ID

P78380

Antibody Clonality

Monoclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4C.

Application Notes

FCM: 10 µg/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

GTX54456 Datasheet

Price

£386.00

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Quantity
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