Catalogue Number: GTX54458-GTX
| Manufacturer: | GeneTex |
| Preservative: | 0.02% Sodium azide|0.02% Sodium azide |
| Molecular Weight: | 125 |
| Physical state: | Liquid |
| Type: | Monoclonal Primary Antibody - Unconjugated |
| Alias: | CD163,CD163 molecule,M130,MM130,SCARI1 |
| Shipping Condition: | Blue Ice |
| Storage Condition: | 2-8°C |
| Unit(s): | 50 ug |
| Host name: | Mouse |
| Clone: | RM3/1 |
| Isotype: | IgG1 |
| Immunogen: | Human monocytes (epitope recognized SRCR domain 9) |
| Application: | FC, ICC, IF, IHC-P, IP, WB, IHC-Fr, NT, Inh |
Description: The protein encoded by this gene is a member of the scavenger receptor cysteine-rich (SRCR) superfamily, and is exclusively expressed in monocytes and macrophages. It functions as an acute phase-regulated receptor involved in the clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages, and may thereby protect tissues from free hemoglobin-mediated oxidative damage. This protein may also function as an innate immune sensor for bacteria and inducer of local inflammation. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011]
Q86VB7
CD163
9332
100 ug/ml
125
Purified
Monoclonal
For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption
WB: 0.4 µg/ml. ICC/IF: 4 µg/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
The monoclonal antibody RM3/1 can be used for macrophage phenotyping.
Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4C.