CD163 antibody [RM3/1]

Catalogue Number: GTX54458-GTX

Manufacturer:GeneTex
Preservative:0.02% Sodium azide|0.02% Sodium azide
Molecular Weight:125
Physical state:Liquid
Type:Monoclonal Primary Antibody - Unconjugated
Alias:CD163,CD163 molecule,M130,MM130,SCARI1
Shipping Condition:Blue Ice
Storage Condition:2-8°C
Unit(s): 50 ug
Host name: Mouse
Clone: RM3/1
Isotype: IgG1
Immunogen: Human monocytes (epitope recognized SRCR domain 9)
Application: FC, ICC, IF, IHC-P, IP, WB, IHC-Fr, NT, Inh

Description

Description: The protein encoded by this gene is a member of the scavenger receptor cysteine-rich (SRCR) superfamily, and is exclusively expressed in monocytes and macrophages. It functions as an acute phase-regulated receptor involved in the clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages, and may thereby protect tissues from free hemoglobin-mediated oxidative damage. This protein may also function as an innate immune sensor for bacteria and inducer of local inflammation. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011]

Additional Text

Uniprot ID

Q86VB7

Gene Name

CD163

Gene ID

9332

Concentration

100 ug/ml

Molecular Weight

125

Purification

Purified

Antibody Clonality

Monoclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Application Notes

WB: 0.4 µg/ml. ICC/IF: 4 µg/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Short Description

The monoclonal antibody RM3/1 can be used for macrophage phenotyping.

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4C.