MASP3 antibody [38:12-3]

Catalogue Number: GTX54476-GTX

Manufacturer:GeneTex
Preservative:0.02% Sodium azide|0.02% Sodium azide
Molecular Weight:79
Physical state:Liquid
Type:Monoclonal Primary Antibody - Unconjugated
Alias:CRARF,CRARF1,MAP1,MASP,MASP1,MASP3,MAp44,PRSS5,RaRF,mannan binding lectin serine peptidase 1,3MC1
Shipping Condition:Blue Ice
Storage Condition:2-8°C
Unit(s): 50 ug
Host name: Rat
Clone: 38:12-3
Isotype: IgG2a
Immunogen:
Application: ELISA, WB

Description

Description: This gene encodes a serine protease that functions as a component of the lectin pathway of complement activation. The complement pathway plays an essential role in the innate and adaptive immune response. The encoded protein is synthesized as a zymogen and is activated when it complexes with the pathogen recognition molecules of lectin pathway, the mannose-binding lectin and the ficolins. This protein is not directly involved in complement activation but may play a role as an amplifier of complement activation by cleaving complement C2 or by activating another complement serine protease, MASP-2. The encoded protein is also able to cleave fibrinogen and factor XIII and may may be involved in coagulation. A splice variant of this gene which lacks the serine protease domain functions as an inhibitor of the complement pathway. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Apr 2010]

Additional Text

Gene ID

5648

Gene Name

MASP1

Uniprot ID

P48740

Concentration

100 ug/ml

Molecular Weight

79

Purification

Purified

Antibody Clonality

Monoclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4C.