Src (phospho Tyr416) antibody (Alexa Fluor 488)

Catalogue Number: GTX54529-GTX

Manufacturer:GeneTex
Preservative:0.05% Sodium azide|0.05% Sodium azide
Molecular Weight:60
Physical state:Liquid
Type:Polyclonal Primary Antibody - Conjugated
Alias:SRC proto-oncogene, non-receptor tyrosine kinase , ASV , SRC1 , THC6 , c-SRC , p60-Src
Shipping Condition:Blue Ice
Unit(s): 100 ul
Host name: Rabbit
Clone:
Isotype: IgG
Immunogen: This antibody was produced against a chemically synthesized phosphopeptide derived from the region of Src that contains tyrosine 416. The antibody was affinity purified by sequential epitope-specific chromatography, then conjugated to Alexa Fluor 488. The Tyr418 of human Src is equivalent to Tyr416 of chicken Src.
Application: ICC, IF, WB

Description

Description: This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]

Additional Text

Gene Name

SRC

Gene ID

6714

Uniprot ID

P12931

Molecular Weight

60

Purification

Purified

Antibody Clonality

Polyclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Modification

Phosphorylated, Tyr416

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles. Protect from light.