Optineurin antibody
Catalogue Number: GTX54617-GTX
GTX54617 Image
GTX54617 Image
GTX54617 Image
GTX54617 Image
IP analysis of mouse heart cell lysate using GTX54617 Optineurin antibody. Antibody amount : 3µg / 25µg lysate Dilution : 1:1000
GTX54617 Image
WB analysis of various sample lysates using GTX54617 Optineurin antibody. Dilution : 1:1000 Loading : 25µg per lane
GTX54617 Image
IHC-P analysis of human liver cancer tissue using GTX54617 Optineurin antibody. Dilution : 1:100
| Manufacturer: | GeneTex |
| Preservative: | 0.02% Sodium azide|0.02% Sodium azide |
| Molecular Weight: | 66 |
| Physical state: | Liquid |
| Type: | Polyclonal Primary Antibody - Unconjugated |
| Alias: | optineurin , ALS12 , FIP2 , GLC1E , HIP7 , HYPL , NRP , TFIIIA-INTP |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ug |
| Host name: | Rabbit |
| Clone: | |
| Isotype: | IgG |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-577 of human OPTN (NP_068815.2). |
| Application: | IHC-P, IP, WB |
Description
Description: This gene encodes the coiled-coil containing protein optineurin. Optineurin may play a role in normal-tension glaucoma and adult-onset primary open angle glaucoma. Optineurin interacts with adenovirus E3-14.7K protein and may utilize tumor necrosis factor-alpha or Fas-ligand pathways to mediate apoptosis, inflammation or vasoconstriction. Optineurin may also function in cellular morphogenesis and membrane trafficking, vesicle trafficking, and transcription activation through its interactions with the RAB8, huntingtin, and transcription factor IIIA proteins. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Jul 2008]
Additional Text
Gene Name
OPTN
Uniprot ID
Q96CV9
Purification
Affinity Purified
Gene ID
10133
Molecular Weight
66
Antibody Clonality
Polyclonal
Note
For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption
Application Notes
WB: 1:500 - 1:2000. IHC-P: 1:50 - 1:200. IP: 1:50 - 1:200. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Storage Note
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
GTX54617 Datasheet
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