Dectin-2 antibody

Catalogue Number: GTX54664-GTX

Manufacturer:GeneTex
Preservative:no preservative|No preservative
Molecular Weight:24
Physical state:Liquid
Type:Polyclonal Primary Antibody - Unconjugated
Alias:C-type lectin domain containing 6A , CLEC4N , CLECSF10 , dectin-2
Shipping Condition:Blue Ice
Unit(s): 100 ul
Host name: Rabbit
Clone:
Isotype: IgG
Immunogen: Human Dectin-2.
Application: FC, ICC, IF, IHC

Description

Description: The protein encoded by this gene is a type II membrane receptor with an extracellular C-type lectin-like domain fold. The extracellular portion binds structures with a high mannose content and has been shown to recognize several pathogens, including C. elegans, S. cerevisiae, M. tuberculosis, C. neoformans, and house dust mite. When stimulated, the encoded protein initiates signalling through the CARD9-Bcl10-Malt1 pathway, leading to the induction of cytokines. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2015]

Additional Text

Gene Name

CLEC6A

Gene ID

93978

Uniprot ID

Q6EIG7

Antibody Clonality

Polyclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Application Notes

FACS: 1:200 IF: 1:100 IHC: 1:200

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.