HCN2 antibody
Catalogue Number: GTX54824-GTX
GTX54824 Image
GTX54824 Image
GTX54824 Image
GTX54824 Image
GTX54824 Image
GTX54824 Image
ICC/IF analysis of PFA-fixed rat DRG primary cells using GTX54824 HCN2 antibody. Green : Primary antibody Blue : DNA dye Hoechst 33342 Dilution : 1:100
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IHC-Fr analysis of mouse? hypothalamus tissue using GTX54824 HCN2 antibody. (V = Third ventricle) Panel A : HCN2 (red) appears in cells of the paraventricular nucleus (PVN, arrows). Panel B : Staining of paraventricular nerve cells with mouse anti-calcium binding protein (CBD28k, green). Panel C : Merge of HCN2 and CBD28k demonstrates some co-localization.
GTX54824 Image
IHC-Fr analysis of rat cerebellum tissue using GTX54824 HCN2 antibody. Panel A : HCN2 (red) appears in Purkinje cells (arrows). Panel B : Staining of astrocytes with mouse anti-glial fibrillary acidic protein (GFAP, green) demonstrates the restriction of HCN2 to neuronal cell bodies. Panel C : Merge of HCN2 and GFAP images demonstrates the respective localization of these proteins.
GTX54824 Image
IHC-Fr analysis of mouse thalamus tissue using GTX54824 HCN2 antibody. Panel A : Staining of HCN4 (green) appears in the ventral posterior thalamic nucleus (VPL). Panel B : In the same section as in A, staining of HCN2 (red) appears in the ventral posterior thalamic nucleus (VPL) and also in the reticular thalamic nucleus (RT). The area between these thalamic nuclei (star) is white matter and neither protein is expressed in that region. Panel C : Merged images of A and B.
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WB analysis of rat brain membrane lysate using GTX54824 HCN2 antibody preincubated with or without immunogen peptide. Dilution : 1:200
| Manufacturer: | GeneTex |
| Preservative: | 0.05% Sodium azide|0.05% Sodium azide |
| Molecular Weight: | 97 |
| Physical state: | Liquid |
| Type: | Polyclonal Primary Antibody - Unconjugated |
| Alias: | hyperpolarization activated cyclic nucleotide gated potassium and sodium channel 2 , BCNG-2 , BCNG2 , HAC-1 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 50 ul |
| Host name: | Rabbit |
| Clone: | |
| Isotype: | IgG |
| Immunogen: | Peptide (C)EEAGPAGEPRGSQAS, corresponding to amino acid residues 147-161 (Intracellular, N-terminus) of human HCN2 (Accession : Q9UL51). |
| Application: | ICC, IF, IP, WB, IHC-Fr |
Description
Description: The protein encoded by this gene is a hyperpolarization-activated cation channel involved in the generation of native pacemaker activity in the heart and in the brain. The encoded protein is activated by cAMP and can produce a fast, large current. Defects in this gene were noted as a possible cause of some forms of epilepsy. [provided by RefSeq, Jan 2017]
Additional Text
Gene Name
HCN2
Gene ID
610
Uniprot ID
Q9UL51
Concentration
0.8 mg/ml
Purification
Affinity Purified
Antibody Clonality
Polyclonal
Note
For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption
Molecular Weight
97
Storage Note
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
GTX54824 Datasheet
SUPPORT
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DELIVERY
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