STIM1 antibody
Catalogue Number: GTX54855-GTX
GTX54855 Image
GTX54855 Image
GTX54855 Image
GTX54855 Image
GTX54855 Image
IHC-P analysis of rat stomach tissue using GTX54855 STIM1 antibody. STIM1 is expressed in the parietal cells of the gastric mucosa (arrows). Hematoxilin is used as the counterstain. Dilution : 1:100
GTX54855 Image
WB analysis of RBL (lanes 1 and 4), HL-60 (lanes 2 and 5), and Jurkat (lanes 3 and 6) cell lysates using GTX54855 STIM1 antibody preincubated with or without immunogen peptide. Dilution : 1:1000
GTX54855 Image
Live cell imaging analysis of live rat RBL cells using GTX54855 STIM1 antibody. Panel A : Primary antibody (Orange) Panel B : Hoechst 33342 for nuclear staining (blue) Panel C : Merged images of Panel A and B Dilution : 1:50
GTX54855 Image
FACS analysis of RBL (A) and Jurkat (B) cells using GTX54855 STIM1 antibody. Black : Unstained cell Green : Cell staining with primary antibody Antibody amount : 5-10 µg antibody / 0.5-1 x 10? ?cells
| Manufacturer: | GeneTex |
| Preservative: | 0.05% Sodium azide|0.05% Sodium azide |
| Molecular Weight: | 77 |
| Physical state: | Liquid |
| Type: | Polyclonal Primary Antibody - Unconjugated |
| Alias: | stromal interaction molecule 1 , D11S4896E , GOK , IMD10 , STRMK , TAM , TAM1 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 50 ul |
| Host name: | Rabbit |
| Clone: | |
| Isotype: | IgG |
| Immunogen: | Peptide CHSEDEKLSFEAVR, corresponding to amino acid residues 56-69 (STIM1 expressed on the plasma membrane: Extracellular, N-terminus st IM1 expressed on th e ER: Luminal, N-terminus) of human STIM1 (Accession : Q13586). |
| Application: | FC, ICC, IF, IHC-P, IP, WB, LCImg |
Description
Description: This gene encodes a type 1 transmembrane protein that mediates Ca2+ influx after depletion of intracellular Ca2+ stores by gating of store-operated Ca2+ influx channels (SOCs). It is one of several genes located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocrotical carcinoma, and lung, ovarian, and breast cancer. This gene may play a role in malignancies and disease that involve this region, as well as early hematopoiesis, by mediating attachment to stromal cells. Mutations in this gene are associated with fatal classic Kaposi sarcoma, immunodeficiency due to defects in store-operated calcium entry (SOCE) in fibroblasts, ectodermal dysplasia and tubular aggregate myopathy. This gene is oriented in a head-to-tail configuration with the ribonucleotide reductase 1 gene (RRM1), with the 3' end of this gene situated 1.6 kb from the 5' end of the RRM1 gene. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, May 2013]
Additional Text
Gene Name
STIM1
Uniprot ID
Q13586
Concentration
0.45 mg/ml
Gene ID
6786
Purification
Affinity Purified
Molecular Weight
77
Antibody Clonality
Polyclonal
Note
For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption
Storage Note
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
GTX54855 Datasheet
SUPPORT
outstanding technical support
PRODUCT
we offer a full product guarantee
DELIVERY
we offer free delivery to UK universities and non profit organisations