alpha Synuclein (phospho Ser129) antibody
Catalogue Number: GTX54991-GTX
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GTX54991 Image
GTX54991 Image
GTX54991 Image
GTX54991 Image
GTX54991 Image
GTX54991 Image
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ICC/IF analysis of formalin-fixed HEK293T cells using GTX54991 alpha Synuclein (phospho Ser129) antibody. Red : Primary antibody Blue : DAPI Permeabilization : 0.1% Triton X-100 in TBS for 5-10 minutes
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IHC-P analysis of formalin fixed human prostate cancer tissue section using GTX54991 alpha Synuclein (phospho Ser129) antibody. Antigen retrieval : Heat mediated antigen retrieval with sodium citrate buffer (pH 6.0)
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WB analysis of HEK293T (A), mouse brain (B) whole cell lysates using GTX54991 alpha Synuclein (phospho Ser129) antibody.
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The data was published in the 2022 in Front Immunol. PMID: 35911740
GTX54991 Image
The data was published in the journal Front Pharmacol in 2020. PMID: 32180729
GTX54991 Image
The data was published in the journal Front Pharmacol in 2020. PMID: 32180729
GTX54991 Image
The data was published in the journal Front Pharmacol in 2020. PMID: 32180729
| Manufacturer: | GeneTex |
| Preservative: | 0.01% Sodium azide |
| Molecular Weight: | 14 |
| Physical state: | Liquid |
| Type: | Polyclonal Primary Antibody - Unconjugated |
| Alias: | synuclein alpha , NACP , PARK1 , PARK4 , PD1 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul |
| Host name: | Rabbit |
| Clone: | |
| Isotype: | IgG |
| Immunogen: | KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of alpha Synuclein. The exact sequence is proprietary. |
| Application: | ICC, IF, IHC-P, WB, IHC-Fr |
Description
Description: Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Alternatively spliced transcripts encoding different isoforms have been identified for this gene. [provided by RefSeq, Feb 2016]
Additional Text
Gene ID
6622
Gene Name
SNCA
Uniprot ID
P37840
Purification
Affinity Purified
Modification
Phosphorylated, Ser129
Antibody Clonality
Polyclonal
Note
For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption
Molecular Weight
14
Application Notes
WB: 1:500 - 1:1000. ICC/IF: 1:100 - 1:500. IHC-P: 1:100 - 1:200. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Storage Note
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
GTX54991 Datasheet
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