alpha Actinin 1 antibody [AT1D10]
Catalogue Number: GTX57633-GTX
GTX57633 Image
GTX57633 Image
GTX57633 Image
GTX57633 Image
ICC/IF analysis of Balb/3T3 cells using GTX57633 alpha Actinin 1 antibody. Blue: DAPI Green: Primary antibody Dilution: 1:100
GTX57633 Image
WB analysis of various samples using GTX57633 alpha Actinin 1 antibody. Lane 1 : PC-3 whole cell lysate Lane 2 : A549 whole cell lysate Loading : 40 µg Dilution : 1:1000
GTX57633 Image
FACS analysis of HeLa cells using GTX57633 alpha Actinin 1 antibody. Cell Number: 1 x 10? cells Red: Primary antibody Antibody amount: 2-5 µg
| Manufacturer: | GeneTex |
| Preservative: | 0.02% Sodium azide|0.02% Sodium azide |
| Molecular Weight: | 103 |
| Physical state: | Liquid |
| Type: | Monoclonal Primary Antibody - Unconjugated |
| Alias: | actinin alpha 1 , ACTN1 , BDPLT15 , alpha Actinin 1 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul |
| Host name: | Mouse |
| Clone: | AT1D10 |
| Isotype: | IgG2a |
| Immunogen: | The clone AT1D10 is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human ACTN3 protein. |
| Application: | FC, ICC, IF, WB |
Description
Description: Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a nonmuscle, cytoskeletal, alpha actinin isoform and maps to the same site as the structurally similar erythroid beta spectrin gene. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Additional Text
Gene Name
ACTN1
Uniprot ID
P12814
Gene ID
87
Molecular Weight
103
Purification
Protein A purified
Antibody Clonality
Monoclonal
Note
For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption
Concentration
1 mg/ml
Storage Note
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
GTX57633 Datasheet
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