alpha Actinin 1 antibody [AT1D10]
Catalogue Number: GTX57633-GTX
GTX57633 Image
GTX57633 Image
GTX57633 Image
GTX57633 Image
FACS analysis of HeLa cells using GTX57633 alpha Actinin 1 antibody. Cell Number: 1 x 10⁶ cells Red: Primary antibody Antibody amount: 2-5 µg
GTX57633 Image
ICC/IF analysis of Balb/3T3 cells using GTX57633 alpha Actinin 1 antibody. Blue: DAPI Green: Primary antibody Dilution: 1:100
GTX57633 Image
WB analysis of various samples using GTX57633 alpha Actinin 1 antibody. Lane 1 : PC-3 whole cell lysate Lane 2 : A549 whole cell lysate Loading : 40 µg Dilution : 1:1000
| Manufacturer: | GeneTex |
| Preservative: | 0.02% Sodium azide |
| Physical state: | Liquid |
| Type: | Monoclonal Primary Antibody - Unconjugated |
| Alias: | actinin alpha 1 , ACTN1 , BDPLT15 , alpha Actinin 1 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul |
| Host name: | Mouse |
| Clone: | AT1D10 |
| Isotype: | IgG2a |
| Immunogen: | The clone AT1D10 is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human ACTN3 protein. |
| Application: | FACS, ICC, IF, WB |
Description
Description: Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a nonmuscle, cytoskeletal, alpha actinin isoform and maps to the same site as the structurally similar erythroid beta spectrin gene. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Additional Text
Concentration
1 mg/ml
Gene Name
ACTN1
Uniprot ID
P12814
Gene ID
87
Molecular Weight
103
Purification
Protein A purified
Antibody Clonality
Monoclonal
Note
For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption
GTX57633 Datasheet
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