Glucokinase antibody, N-term

Catalogue Number: GTX59598-GTX

Manufacturer:	GeneTex
Preservative:	0.09% sodium azide
Molecular Weight:	52
Physical state:	Liquid
Type:	Polyclonal Primary Antibody - Unconjugated
Alias:	glucokinase , FGQTL3 , GK , GLK , HHF3 , HK4 , HKIV , HXKP , LGLK , MODY2
Shipping Condition:	Blue Ice
Unit(s):	50 ug
Host name:	Rabbit
Clone:
Isotype:	IgG
Immunogen:	Synthetic peptide selected from the N-terminal region of human GCK
Application:	ELISA, FC, ICC, IF, IHC-P, WB, IHC

Overview
Datasheets

Description

Description: This gene encodes a member of the hexokinase family of proteins. Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. In contrast to other forms of hexokinase, this enzyme is not inhibited by its product glucose-6-phosphate but remains active while glucose is abundant. The use of multiple promoters and alternative splicing of this gene result in distinct protein isoforms that exhibit tissue-specific expression in the pancreas and liver. In the pancreas, this enzyme plays a role in glucose-stimulated insulin secretion, while in the liver, this enzyme is important in glucose uptake and conversion to glycogen. Mutations in this gene that alter enzyme activity have been associated with multiple types of diabetes and hyperinsulinemic hypoglycemia. [provided by RefSeq, Aug 2017]

Additional Text

Gene Name

GCK

Gene ID

2645

Uniprot ID

P35557

Concentration

0.25 mg/ml

Purification

Affinity Purified

Molecular Weight

Antibody Clonality

Polyclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Application Notes

WB: 0.5-2.5 µg/ml. ELISA: 0.25 µg/ml. IHC: 2.5-5.0 µg/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.

GTX59598 Datasheet

Price

£374.00

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Quantity
Unit Size

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