Cyclin D2 antibody

Catalogue Number: GTX60131-GTX

Manufacturer:	GeneTex
Preservative:	0.09% Sodium azide
Physical state:	Liquid
Type:	Polyclonal Primary Antibody - Unconjugated
Alias:	cyclin D2 , KIAK0002 , MPPH3
Shipping Condition:	Blue Ice
Unit(s):	100 ul
Host name:	Rabbit
Clone:
Isotype:	IgG
Immunogen:	KLH conjugated synthetic peptide derived from human Cyclin D2(150-200).
Application:	ICC, IF, IHC-P, WB

Overview
Datasheets

Description

Description: The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with CDK4 or CDK6 and functions as a regulatory subunit of the complex, whose activity is required for cell cycle G1/S transition. This protein has been shown to interact with and be involved in the phosphorylation of tumor suppressor protein Rb. Knockout studies of the homologous gene in mouse suggest the essential roles of this gene in ovarian granulosa and germ cell proliferation. High level expression of this gene was observed in ovarian and testicular tumors. Mutations in this gene are associated with megalencephaly-polymicrogyria-polydactyly-hydrocephalus syndrome 3 (MPPH3). [provided by RefSeq, Sep 2014]

Additional Text

Gene Name

CCND2

Uniprot ID

P30279

Concentration

1 mg/ml

Gene ID

894

Purification

Protein A purified

Antibody Clonality

Polyclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Molecular Weight

Application Notes

ICC/IF: 1:50-200. IHC-P: 1:50-400. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

GTX60131 Datasheet

Price

£373.00

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