DLK1 antibody

Catalogue Number: GTX60309-GTX

Manufacturer:GeneTex
Preservative:0.09% sodium azide
Molecular Weight:41
Physical state:Liquid
Type:Polyclonal Primary Antibody - Unconjugated
Alias:delta like non-canonical Notch ligand 1 , DLK , DLK-1 , Delta1 , FA1 , PREF1 , Pref-1 , ZOG , pG2
Shipping Condition:Blue Ice
Unit(s): 100 ul
Host name: Rabbit
Clone:
Isotype: IgG
Immunogen: KLH conjugated synthetic peptide derived from human DLK1(260-305).
Application: IHC-P, WB, IHC-Fr

Description

Description: This gene encodes a transmembrane protein containing six epidermal growth factor repeats. The protein is involved in the differentiation of several cell types, including adipocytes; it is also thought to be a tumor suppressor. It is one of several imprinted genes located in a region of on chr 14q32. Certain mutations in this imprinted region can cause phenotypes similar to maternal and paternal uniparental disomy of chromosome 14 (UPD14). This gene is expressed from the paternal allele. A polymorphism within this gene has been associated with child and adolescent obesity. The mode of inheritance for this polymorphism is polar overdominance; this non-Mendelian inheritance pattern was first described in sheep with the callipyge phenotype, which is characterized by muscle hypertrophy and decreased fat mass. [provided by RefSeq, Mar 2010]

Additional Text

Gene Name

DLK1

Gene ID

8788

Purification

Protein A purified

Uniprot ID

P80370

Antibody Clonality

Polyclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Molecular Weight

41

Concentration

1 mg/ml

Application Notes

WB: 1:300-1000. IHC-P: 1:50-400. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.