Pyruvate dehydrogenase kinase 1 / PDK1 antibody [4A11]

Catalogue Number: GTX60386-GTX

Manufacturer:	GeneTex
Preservative:	0.03% Sodium azide
Molecular Weight:	49
Physical state:	Liquid
Type:	Monoclonal Primary Antibody - Unconjugated
Alias:	pyruvate dehydrogenase kinase 1
Shipping Condition:	Blue Ice
Unit(s):	100 ul
Host name:	Mouse
Clone:	4A11
Isotype:	IgG1
Immunogen:	Purified recombinant fragment of human PDK1 expressed in E. Coli.
Application:	ELISA, FC, ICC, IF, IHC-P, WB

Overview
Datasheets

Description

Description: Pyruvate dehydrogenase (PDH) is a mitochondrial multienzyme complex that catalyzes the oxidative decarboxylation of pyruvate and is one of the major enzymes responsible for the regulation of homeostasis of carbohydrate fuels in mammals. The enzymatic activity is regulated by a phosphorylation/dephosphorylation cycle. Phosphorylation of PDH by a specific pyruvate dehydrogenase kinase (PDK) results in inactivation. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jun 2013]

Additional Text

Gene Name

PDK1

Uniprot ID

Q15118

Gene ID

5163

Molecular Weight

Purification

Unpurified

Antibody Clonality

Monoclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.

Application Notes

WB: 1/500 - 1/2000. ICC/IF: 1/200 - 1/1000. IHC-P: 1/200 - 1/1000. FCM: 1/200 - 1/400. ELISA: 1/10000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

GTX60386 Datasheet

GTX60386 Reference

Price

£410.00

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