CRTC3 antibody [5G9]

Catalogue Number: GTX60400-GTX

Manufacturer:GeneTex
Preservative:0.03% Sodium azide
Molecular Weight:67
Physical state:Liquid
Type:Monoclonal Primary Antibody - Unconjugated
Alias:CREB regulated transcription coactivator 3 , TORC-3 , TORC3
Shipping Condition:Blue Ice
Unit(s): 100 ul
Host name: Mouse
Clone: 5G9
Isotype: IgG1
Immunogen: Purified recombinant fragment of human CRTC3 expressed in E. Coli.
Application: ELISA, ICC, IF, IHC-P, WB

Description

Description: This gene is a member of the CREB regulated transcription coactivator gene family. This family regulates CREB-dependent gene transcription in a phosphorylation-independent manner and may be selective for cAMP-responsive genes. The protein encoded by this gene may induce mitochondrial biogenesis and attenuate catecholamine signaling in adipose tissue. A translocation event between this gene and Notch coactivator mastermind-like gene 2, which results in a fusion protein, has been reported in mucoepidermoid carcinomas. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Jul 2012]

Additional Text

Gene ID

64784

Uniprot ID

Q6UUV7

Gene Name

CRTC3

Molecular Weight

67

Purification

Unpurified

Antibody Clonality

Monoclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Application Notes

WB: 1/500 - 1/2000. ICC/IF: 1/200 - 1/1000. IHC-P: 1/200 - 1/1000. ELISA: 1/10000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.