RUNX1 antibody [5A1]

Catalogue Number: GTX60402-GTX

Manufacturer:GeneTex
Preservative:0.03% Sodium azide
Molecular Weight:49
Physical state:Liquid
Type:Monoclonal Primary Antibody - Unconjugated
Alias:runt related transcription factor 1 , AML1 , AML1-EVI-1 , AMLCR1 , CBF2alpha , CBFA2 , EVI-1 , PEBP2aB , PEBP2alpha
Shipping Condition:Blue Ice
Unit(s): 100 ul
Host name: Mouse
Clone: 5A1
Isotype: IgG1
Immunogen: Synthesized peptide of human RUNX1.
Application: ELISA, ICC, IF, WB

Description

Description: Core binding factor (CBF) is a heterodimeric transcription factor that binds to the core element of many enhancers and promoters. The protein encoded by this gene represents the alpha subunit of CBF and is thought to be involved in the development of normal hematopoiesis. Chromosomal translocations involving this gene are well-documented and have been associated with several types of leukemia. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Additional Text

Gene ID

861

Gene Name

RUNX1

Uniprot ID

Q01196

Molecular Weight

49

Purification

Unpurified

Antibody Clonality

Monoclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Application Notes

WB: 1/500 - 1/2000. ICC/IF: 1/200 - 1/1000. ELISA: 1/10000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.