BMPR2 antibody [3F6]

Catalogue Number: GTX60415-GTX

Manufacturer:	GeneTex
Preservative:	0.03% Sodium azide
Molecular Weight:	115
Physical state:	Liquid
Type:	Monoclonal Primary Antibody - Unconjugated
Alias:	bone morphogenetic protein receptor type 2 , BMPR-II , BMPR3 , BMR2 , BRK-3 , POVD1 , PPH1 , T-ALK
Shipping Condition:	Blue Ice
Unit(s):	100 ul
Host name:	Mouse
Clone:	3F6
Isotype:	IgG1
Immunogen:	Purified recombinant fragment of human BMPR2 expressed in E. Coli.
Application:	ELISA, ICC, IF, IHC-P, WB

Overview
Datasheets

Description

Description: This gene encodes a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are BMPs, which are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of two different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. Mutations in this gene have been associated with primary pulmonary hypertension, both familial and fenfluramine-associated, and with pulmonary venoocclusive disease. [provided by RefSeq, Jul 2008]

Additional Text

Gene Name

BMPR2

Uniprot ID

Q13873

Gene ID

659

Molecular Weight

115

Purification

Unpurified

Antibody Clonality

Monoclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Application Notes

WB: 1/500 - 1/2000. ICC/IF: 1/200 - 1/1000. IHC-P: 1/200 - 1/1000. ELISA: 1/10000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.

GTX60415 Datasheet

GTX60415 Reference

Price

£410.00

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