GRK2 antibody [3F8]

Catalogue Number: GTX60430-GTX

Manufacturer:	GeneTex
Preservative:	0.03% Sodium azide
Molecular Weight:	80
Physical state:	Liquid
Type:	Monoclonal Primary Antibody - Unconjugated
Alias:	G protein-coupled receptor kinase 2 , ADRBK1 , BARK1 , BETA-ARK1
Shipping Condition:	Blue Ice
Unit(s):	100 ul
Host name:	Mouse
Clone:	3F8
Isotype:	IgG1
Immunogen:	Purified recombinant fragment of human GRK2 expressed in E. Coli.
Application:	ELISA, ICC, IF, IHC-P, WB

Overview
Datasheets

Description

Description: The product of this gene phosphorylates the beta-2-adrenergic receptor and appears to mediate agonist-specific desensitization observed at high agonist concentrations. This protein is an ubiquitous cytosolic enzyme that specifically phosphorylates the activated form of the beta-adrenergic and related G-protein-coupled receptors. Abnormal coupling of beta-adrenergic receptor to G protein is involved in the pathogenesis of the failing heart. [provided by RefSeq, Jul 2008]

Additional Text

Gene ID

156

Uniprot ID

P25098

Gene Name

GRK2

Molecular Weight

Purification

Unpurified

Antibody Clonality

Monoclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Application Notes

WB: 1/500 - 1/2000. ICC/IF: 1/200 - 1/1000. IHC-P: 1/200 - 1/1000. ELISA: 1/10000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.

GTX60430 Datasheet

Price

£410.00

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