OTX2 antibody [1H12C4B5]
Catalogue Number: GTX60448-GTX
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ELISA analysis of antigen using GTX60448 OTX2 antibody [1H12C4B5]. Red : Control antigen 100ng Purple : Antigen 10ng Green : Antigen 50ng Blue : Antigen 100ng
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FACS analysis of HepG2 cells using GTX60448 OTX2 antibody [1H12C4B5]. Green : OTX2 Purple : negative control
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ICC/IF analysis of HepG2 cells using GTX60448 OTX2 antibody [1H12C4B5]. Green : OTX2 Red: Actin filaments
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IHC-P analysis of prostate tissue (left) and colon cancer tissue (right) using GTX60448 OTX2 antibody [1H12C4B5].
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WB analysis of human OTX2 (AA: 40-297) recombinant protein using GTX60448 OTX2 antibody [1H12C4B5].
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WB analysis of HepG2 (1), Jurkat (2), and NTERA-2 (3) cell lysate using GTX60448 OTX2 antibody [1H12C4B5].
| Manufacturer: | GeneTex |
| Preservative: | 0.03% Sodium azide |
| Molecular Weight: | 32 |
| Physical state: | Liquid |
| Type: | Monoclonal Primary Antibody - Unconjugated |
| Alias: | orthodenticle homeobox 2 , CPHD6 , MCOPS5 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul |
| Host name: | Mouse |
| Clone: | 1H12C4B5 |
| Isotype: | IgG1 |
| Immunogen: | Purified recombinant fragment of human OTX2 expressed in E. Coli. |
| Application: | ELISA, FC, ICC, IF, IHC-P, WB |
Description
Description: This gene encodes a member of the bicoid subfamily of homeodomain-containing transcription factors. The encoded protein acts as a transcription factor and plays a role in brain, craniofacial, and sensory organ development. The encoded protein also influences the proliferation and differentiation of dopaminergic neuronal progenitor cells during mitosis. Mutations in this gene cause syndromic microphthalmia 5 (MCOPS5) and combined pituitary hormone deficiency 6 (CPHD6). This gene is also suspected of having an oncogenic role in medulloblastoma. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Pseudogenes of this gene are known to exist on chromosomes two and nine. [provided by RefSeq, Jul 2012]
Additional Text
Gene Name
OTX2
Molecular Weight
32
Gene ID
5015
Purification
Unpurified
Uniprot ID
P32243
Antibody Clonality
Monoclonal
Note
For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption
Storage Note
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
Application Notes
WB: 1/500 - 1/2000. ICC/IF: 1/200 - 1/1000. IHC-P: 1/200 - 1/1000. FCM: 1/200 - 1/400. ELISA: 1/10000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
GTX60448 Datasheet
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DELIVERY
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