CD105 antibody [3A9]

Catalogue Number: GTX60452-GTX

Manufacturer:GeneTex
Preservative:0.03% Sodium azide
Molecular Weight:71
Physical state:Liquid
Type:Monoclonal Primary Antibody - Unconjugated
Alias:endoglin , END , HHT1 , ORW1
Shipping Condition:Blue Ice
Unit(s): 100 ul
Host name: Mouse
Clone: 3A9
Isotype: IgG1
Immunogen: Purified recombinant fragment of human CD105 expressed in E. Coli.
Application: ELISA, FC, ICC, IF, IHC-P, WB

Description

Description: This gene encodes a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds to the beta1 and beta3 peptides with high affinity. Mutations in this gene cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia. This gene may also be involved in preeclampsia and several types of cancer. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2013]

Additional Text

Gene Name

ENG

Gene ID

2022

Molecular Weight

71

Purification

Unpurified

Uniprot ID

P17813

Antibody Clonality

Monoclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.

Application Notes

WB: 1/500 - 1/2000. ICC/IF: 1/200 - 1/1000. IHC-P: 1/200 - 1/1000. FCM: 1/200 - 1/400. ELISA: 1/10000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.